Audit Checklist for Engineering Department: Here is the tentative Audit Checklist Engineering Department. You can follow the checking point during auditing process at Engineering and Maintenance Department.
Approved Departmental Organogram.
Area monitoring for Temperature/Relative Humidity/Differential Pressure.
BMS[Building Management Systems] Operation Record Logbook/Data Backup/Data storage/Authorized User List
Breakdown Maintenance Record.
Boiler Certificate and Boiler Operator Registration Number.
Buffer stock of Filter with identification Mark.
Calibration Tag with due date on equipment’s.
Compressed Air Validation Record.
Deviation Management Record.
Departmental Objective.
Dust collector SOP, Record, Disposal and Operation Logbook.
Drawing of Technical Floor and Production Floor[With Man/Machine Flow].
Equipment’s Calibration schedule with frequency.
ETP process flow diagram.
Filter Integrity Test Record.
Filter Changing record.
HVAC Validation Record.
Incinerator Operation Logbook/Third party agreement for Incineration.
IQ, OQ, PQ record for new equipment’s.
List of Personnel and their Job description.
List SOP’s.
List of Equipment’s.
List of Spare Parts.
Labelling of all critical machine/Line/Instruments e.g. Boiler, Underground Water Line, Diesel Tank, Gas Cylinder etc.
Logbook for Operation of ETP.
Marking of Clean and Unclean Filter.
Maintenance & Service Card/Record
Personal Protective Equipment list for maintenance of any equipment’s.
Previous Audit Report.
Previous Audit Pending Issue.
Preventive Maintenance Schedule.
Record keeping during CAPA procedure.
Retention Time of documents.
RSD[room schematic diagram] and RDS[Room Data Sheet] record.
Sanitation Record of Water system.
SOP for LOTO [Lock Out, Tag Out] Procedure.
SOP for Color Code.
SOP display on working place/Area/Machine Location.
Status label for equipment’s/Critical Spare parts/ Clean Filters.
Storage Record of critical Spare Parts.
Third party Agreement for Calibration of Equipment’s.
Training Record of Personnel.
Training Need Assessment.
Temperature Mapping.
Under Maintenance /Under Installation/Out of order Identification Label.
Yearly Calibration Schedule with frequency.
Yearly Training Calendar.
Work Permit Record for equipment’s maintenance.
Water System Drawing with user point identification.
Water sampling point Identification.
This all about the Audit Checklist for Engineering Department [but not limited to]. You can treat this list as Internal Audit/ Self-Inspection Checklist or any checklist to find out the lacking of respective department.
Audit Checklist: Here is the tentative Audit checklist [Internal Audit/Self Inspection Checklist] for Quality Control Department. You may follow the below list at the time of Audit [Internal Audit/Self Inspection] for Quality Control Department-
1. Approved Departmental Organogram.
2. Approved vendor List of Raw and Packaging Materials.
3. Acceptance Record of Raw Material and Packaging Material.
4. Approval or Rejection of Materials and Products.
5. Controlling method of
Purchase
Primary Packaging and
Printed Packaging Materials
6. Data Verification based on Logbook and Chromatograms.
7. Document retrieval and achieving Procedure.
8. Collection of retained sample and retrieval system.
9. Certificate of analysis.
Primary data
Checking of calculations
Preservation of primary data
10. Certification of Products for Release.
11. Chemical Reagents consumption records.
12. Calibration Record Keeping for the instruments.
13. Calibration schedule/calendar of instruments.
14. Disinfectant effectiveness testing based on different concentration.
15. Documentation
Material receiving report
Preservation of original data
Final report
Communication with related department e.g- Supply chain, Warehouse, Accounts
16. Health checks for all personnel
Pre-employment
Yearly
Record
17. In-process analysis (Specification & method)
Currently revised
Revision procedure
Validation
Approval
18. Instruments SOPs of operation, maintenance & calibration
Operation Logbook
Calibration
Servicing
Documentation
19. Investigation of Test Failure.
20. Job Responsibilities of all personnel are available.
21. List of Reagents & Solvents.
22. Laboratory Reagents
Identified
Tested
Expiration dated
23. Maintaining of Reference Number for
Specification
Starting materials (both RM & PM)
Finished products
Certificate of Analysis
24. Management of HPLC columns.
25. Method for Identification of each starting materials container.
26. Management of Working Standard/Reference Standard.
27. Management of analytical worksheets.
28. Method Validation of Testing Product.
29. Maintain and storage of HPLC Column and column suitability test.
30. Management of Control Sample.
31. Practice and Record keeping of OSS with action plan.
32. Personnel engaged in analytical activity.
Personnel Hygiene
Lab Coat
33. Prohibited in working area
Smoking
Chewing tobacco
Eating/ Drinking
34. Preparation and record keeping of working standard and volumetric solutions.
35. Record Keeping of
Sampling
Inspection and
Testing procedures
36. Reference Standard
Evaluation
Maintaining
Record Keeping
Logbook Entry
Storage
37. Receiving Record of
Reagents
Chemicals
Culture Media
38. Retesting procedure
39. Received Material
Sampling Plan
Sampled Quantity
40. Real Time & On-going Stability Study Calendar/Schedule.
41. Qualification [DQ, IQ, OQ & PQ] records of Oven.
42. Real Time & On-going Stability Study Sample Receiving Record.
43. Real Time & On-going Stability Study Failure Investigation.
44. Real Time & On-going Stability Study Report Evaluation, Recommendations and Conclusion.
45. Safety
Fire extinguishers-adequacy
First aid-adequacy
Possibility of potential electrical hazards
46. SOP on cleaning
Glass apparatus
General cleaning of department
47. SOP on Material Coding System.
48. SOP on calibration of measurement equipment.
49. SOP on Handling of breakdown of stability chambers.
50. SOP for sampling of
Starting Materials
Bulk Materials and
Finished Products
51. SOP for
Label and labeling system
Packing Materials handling
Handling of the raw material
Reanalysis
Testing of Market Complaints Sample
Testing of Recalled Products
Return products
52. Stability study
List of products under stability study
Stability protocols & reports
Temp. % RH monitoring records of the stability chambers
53. Shelf life extension programme based on Real Time Stability Study.
54. Stability Study Record of Primary packaging materials.
55. Standardization of volumetric solution & documentation.
56. SOP for Sampling and Management of Raw Materials, Packaging materials.
57. Sampling of Water System.
58. Specification & Methods
Currently revised
Revision procedure
Validation
Approval
59. Standard Lab requirement availability
Adequate facilities
Trained persons
Analyst Validation
Approved procedures
60. Standard documented system for
Specification
Sampling
Testing and
Release of materials and products
61. Testing
Physical
Chemical
Microbiological/ Biological
62. Tolerance of Electronic balances.
63. Testing of Validation Batch/Scale Up batch Record.
64. Temperature and Relative Humidity Monitoring Record of Oven Humidity chambers.
6. Calibration & Recording keeping of Micropipette.
7. Calibration records of measuring devices.
8. Calibration record for heating block for BET.
9. Disposal of microorganism, used culture media, used plates etc.
10. Environmental monitoring records.
11. Growth promotion records of media.
12. Environmental Monitoring and Water Analysis Record.
13. Filter integrity tests record for filters of LAF.
14. Incubators calibration Record.
15. LAF Validation schedule.
16. Microbial culture management.
Name of the organisms
ATCC/NCTC numbers
Sub-culturing of organisms
Preservation of microbial culture
17. Master list of SOPs, specifications & methods are updated.
18. Operational Logbooks .
19. Preventive Maintenance schedule for LAF filter cleaning.
20. Record Keeping for Bacterial Endotoxin Test[BET] and Sterility Test.
21. Stock stains available.
22. Testing area.
Adequacy of space
Adequacy of equipment
Cleanliness
23. SOP for
Gowning and De-Gowning Procedure Though the Change Room of Microbiology Area
Management of Water Sampling and Testing
Microbial Disposal of Waste Media
Operation of Colony Counter for Microbiology
Cleaning and Sanitation of Microbiology Laboratory
Operation and Maintenance of Single Door Autoclave
Operation, Calibration and Maintenance of Laminar Air Flow Cabinet
Operation and Maintenance of Bacterial Incubator
Operation and Cleaning Procedure of Oven
Preparation and Preservation of Microbiological Media
24. Temperature charts and records of BOD incubators
25. Validation of autoclave machine
26. Validation of LAF
27. Validation Record of BET kit
28. Water monitoring records
This is all about the Audit Checklist [Internal Audit/Self Inspection Checklist] for Quality Control Department [QC & Microbiology Lab] [but not limited to]
Powder and Granules: here is the brief description of Powder and Granules, You will get the short description of Powder and Granules in this area-
Definition of Powder
Powders, which are finely divided solids, offer versatility in industry and everyday life through easy integration with solvents such as water, facilitating a variety of applications such as pharmaceutical formulations and industrial processes, while being tailored to specific needs and requirements. can be adjusted. This improves human health, comfort and productivity.
Powder, often understood as a finely divided solid substance, has many uses in industry and everyday life. Its versatility lies in the fact that it is easily mixed with suitable solvents such as water or liquids, making it easy to apply in a variety of forms and functions. For example, imagine a powdered drug, a common scenario in the pharmaceutical industry. This powdered drug can be dissolved in a suitable solvent, such as water, to form an orally administrable solution. Alternatively, the powder can be applied topically and used as a powder to treat skin conditions or wounds.
Additionally, the composition of the powder can be made individually depending on each need. Diluents are often added to pharmaceuticals to adjust the density and properties of the powder. For example, liquids contain small amounts of methyl paraben and propyl paraben, typically in a 2 to 3:1 ratio, which is about 0.05% to 0.10% of the total mixture. This combination is classified by the FDA as “generally recognized as safe” (GRAS) for food preservation, ensuring both effectiveness and safety of the final product.
The classification of powders goes beyond their composition to include a variety of uses. For example, powders can be classified according to their use, such as pharmaceutical powders for medical use, cosmetic powders for beauty products, and industrial powders for manufacturing processes. Each classification may have specific requirements and regulations that apply to production and use.
In essence, the definition of Powder goes beyond a simple physical state and embodies a realm of possibility where careful composition and application can lead to innovations that improve human health, comfort, and productivity.
Classification of Powder on the basis of use.
Internal Use Bulk Powder
External Use Bulk Powder
Unit dose or Divided Dose Powder
Internal Use Bulk Powder
The finely divided chemicals or drugs in dry form can be used in internal purpose [Oral Power]
Classifications:
Dry powder inhalers
Effervescent powders
Oral powder
Powder spray
External Use Bulk Powder
The finely divided chemicals or drugs in dry form can be used in External purpose [Dusting Powder] and available in multiple doses[Dusting Powder]
Classification:
Dentifrices
Dusting powders
Insufflations
Unit dose or Divided Dose Powder
The finely divided chemicals or drugs in dry form can be used in internal purpose [Oral Power] but the individual doses are separately wrapped.
Classification
Powder for injection
Effervescent powders
Douche powders
Classification of Powders based on size
Powder can be divided into several categories based on its size.
Macroscopic Powder
Microscopic Powder
Submicron Powder
Nano Powder
Ultrafine Powder
Macroscopic Powder:
These powders have particle sizes ranging from 10 μm (micrometers) to 1000 μm. They are usually visible to the naked eye and are often used in applications where physical properties are important, such as tablet or granule production.
Microscopic Powder:
The particle size of this powder varies from 0.1μm to 10μm. They are invisible to the naked eye and are widely used in pharmaceutical, cosmetics and other industries where fine particles are needed for specific properties.
Submicron Powder:
The particle size of this powder is 0.01μm to 0.1μm. They are very fine and are used in advanced materials, nanotechnology and some medical applications where precise control of particle size is essential.
Nano powder:
This powder has a particle size of less than 100 nanometers (0.1 μm). They exhibit unique properties due to their small size and high surface-to-volume ratio and have applications in fields such as electronics, catalysis, and drug delivery.
Ultrafine Powder:
These powders have particle sizes ranging from 1μm to 100μm, which are finer than macroscopic powders but larger than fine and submicron powders. They are used in a variety of industries including paint, varnish and additive industries.
Classifying powders based on size is important because it affects the properties, behavior, and uses of the powder. Different particle sizes can lead to changes in fluidity, compressibility, surface area and reactivity, among other things. Therefore, understanding and controlling particle size distribution is important in many industries to achieve desired performance and effectiveness.
Mixing of Powders
The use of double tapping technology is essential for accurate mixing of powder ingredients, especially in pharmaceutical manufacturing where precise dosing is important. Known in the pharmaceutical industry for the efficiency of geometric dilution, this technique ensures uniform distribution of ingredients in the mixture.
The process begins with carefully measuring the smallest powdered substances and placing them in a mortar. Then more powder is added to the mortar in equal amounts. After mixing the two ingredients, rub the mixture vigorously until you have a uniform mixture. This rigorous mixing process ensures that each particle of the small ingredient is distributed evenly into the larger mass, preventing potential concentration gradients or uneven dosing.
One of the key principles of geometric dilution is the concept of incremental addition. As the mixing process progresses, each time you add more powder, you actually double the amount of material in the mortar. This incremental concentration ensures consistency and uniformity of the final product by ensuring small ingredients are fully incorporated into the overall mixture.
A practical example of the application of this technology is the development of effective drugs, especially those containing hormonal components. These preparations require precise doses of the active ingredient, which is usually present in small quantities. By using geometric liquids via double tapping technology, pharmaceutical manufacturers can ensure that these powerful compounds are evenly distributed throughout the formulation, reducing the risk of dosage variation and ensuring the safety and efficacy of the final product.
Process Steps
To facilitate homogenization and to prevent stratification the particle size has to be reduced. The process steps is depicted here-
Sieving
Weighing of each ingredient
Mixing
Packaging
General method for preparation of bulk Powders: Geometric dilution
Firstly weigh the Smallest Volume[Powder X] and place into a mortar
Secondly weigh the Large Volume[Powder Y] and place into a separate labeled container
Add the same amount of Powder Y as of same amount of Powder X into the mortar
Use pestle to mix well
Now add the same amount of “Powder Y” as the same amount of Powder as of Mortar then mix with Pestle, continue this process. Every time the powder quantity will be double compare to previous quantity in mortar.
General method for preparation of Divided Powders
Weigh the Active ingredients and diluent accurately.
Arrange trituration of two powers separately before mixing.
The mix the two ingredients with spatulation method.
Place the powders in a surface ensure they are in proper quantity using block and divide method.
Arrange dividing the quantity as per requirement.
Wrap them into individual paper.
Place them into individual container and
Finally label the container.
To dilute the active ingredients of the powder, generally lactose is used to produce the required quantity due to Lactose is colorless, odorless, soluble and also harmless can easily maintain the flow property. The patient who are susceptible to Lactose then Light Kaolin may be used.
Powder calculations
If you are dealing with Powder calculation, you have to calculate at least 1% extra powder to compensate loss during compounding.Always try to take minimum quantity of active ingredients compare to dilution, then minimum weighable quantity is diluted several times.
Advantages of Powders
Powder is more stable compare to liquid dosage form
Very much useful for multiple dosage of single product
Helpful for children and senior citizen
Ensure first rate of bioavailability due to small particle size
Disadvantages of Powders
Unstable in atmospheric conditions
Uniformity dosage failure occur frequently
Not suitable for carry out from here and there.
Shelf life and storage of Internal Powders
Internal powders shelf life is 14 to 30 days
Due to protective packaging proprietary power have longer shelf life
Powder should be store in moisture proof and airtight area.
Shelf life and storage of External Powders
External powders shelf life is 30 days.
If ensure proper packaging then dry power remain stable in longer period of time.
Must be store in a cool and dry place.
Containers for Internal Powders
If powders are prepare extemporaneously then then wrapped powders are often dispensed in paperboard box.
An air tight container is preferable to store internal powder to protect from moisture.
Almost all bulk powders are packed in airtight container.
Containers for External Powders
Glass, metal or plastic containers can be used for storage of external powders. For packaging of propellant and lubricants, pressurized containers are commercially available to ensure proper safety and security.
Labels and advice for Internal Powders
Mix with suitable solvent or supplied solvent if comes with powder container itself otherwise mix indicated amount of water slowly in a divided portion and shake upon addition of divided amount. Don’t add all indicated amount of solvent at a time. Add it gradually in several portion. Bulk powder must be dilute and measure carefully. Bulk powder use for babies can be placed into mouth with a drink
Labels and advice for External Powders
For external use only.
Store in cool and dry place.
Protect from direct sunlight
Uses of Powders
The powder is uses for the following cases-
Used as counter-irritant e.g camphor starch dusting powder.
Used as antimicrobial e.g. Chlorhexidine dusting powder.
Used as antipyretic e.g. ipecacuanha and opium[Dover’s Powder]
Treatment of antacid and anti-flatulent e.g. Magnesium trisilicate
Used as antiseptics i. g. 5% of Povidone-Iodine Powder[Betadine Powder]
Treatment of juvenile arthritis i.e. Ibuprofen powder
Aluminium free baking powder e.g. Rumford
Widely use in Cosmetics and Face Powders
To relief skin burn e.g. prickly heat powders
Protect skin and nappy rashes e.g. Baby powders
Used in dyspepsia e.g. Rhubarb powder
Granules:
Granules are produced by the agglomeration of minute particle produce large free flowing particles. The particle range vary between 4 and 10 mesh size. Most of them are irregular shape but need to produce spherical shape. Granules are the intermediate form of Tablets and Capsules.
What’s the advantage of Granules over Powder?
To avoid powder separation.
To increase the flow of powder.
To increase higher porosity.
To increase the compressibility of powder.
The materials having lightly hygroscopic tendency may adhere and form cake if store in powder form.
Classification of Granules
Granules are classified into following Categories
Coated granules
Effervescent granules
Gastro-resistant granules
Modified release granules
Coated Granules
The granules are undergone single or multilayer coating process with the help of various types of excipient form coated granules use in multi dose preparations. The materials which are used to coat the granules are firstly made solutions or suspensions with suitable solvent may be Organic[Isopropyl Alcohol/Methanol/Metethelene Chloride or Inorganic[Water]. Solvents are generally evaporate during coating process.
Effervescent Granules
The uncoated granules, generally contains acid substances and hydrogen carbonate or carbonate which react instantly with water upon addition with it and release carbon-dioxide. The granules must be dispersed or dissolved with water before administration.
Gastro resistant Granules
The granules that are intended to resist the gastric fluid and release the active ingredients in intestinal fluid well known as delayed release granules. The gastro resistant properties are just attain by coating of suitable materials[Polymer Like-Hydroxypropyl methylcellulose phthalate/vinyl acetate phthalate/Cellulose acetate trimellitate/esters of aleurtic acid/Cellulose acetate phthalate etc.]
Modified release Granules
The granules contains special type of excipients or that is prepared with special procedure are both involved, and designed to altered the rate, the place or time at which the active ingredient release. The modified release granules are two types as Delayed release granules and Prolonged release granules.
Granules preparation Methods
All of the granules are made of mainly in two method
Dry Granulation Method
Wet Granulation Method
Dry Granulation Method
Dry Granulation methods are performed in two ways-
Roller Compactor
Slugging
Roller Compactor:
The dry powder passed through roller compactor then a granulating machine. A Roller compactor is also familiar as roll press, roll compactor use to process fine powder to dense sheet form by forcefully passing through two heavy rotating metal roll running counter to each other.
To attain different forms and textures the surface of the compacting rolls may contain corrugations or pocket indentation and surface of roller compactor may be smooth to do the same. The compacted powder further granulated in a mechanical granulator to get uniform particle.
Slugging
During slugging process the pressure may be difference between 8,000 to 12,000 lb to form large tablets based on the physical characteristics of powder form. The produced slug may be in flat faced in 1 inch diameter.
The resulted slugs are granulated to produce desired particle size used to produce tablets and capsule. During dry granulation, some fine particles are produced that is not agglomerated, the fines particle are collected, separated finally reprocessed.
Wet Granulation Method
In the wet granulation method the, paste prepared by moisten the powder or powder mixture then the paste passed through the specific screen of mesh size and produced desired size of granules. Granules are then placed on tray for drying and dried it by heat or air. The granules are periodically moves on the drying tray to avoid adhesion to outsized mass.
The other type of wet granulation method is known as fluid bed granulation processing (also known as agglomeration) where particles are placed on conical shape of equipment and liquid excipient spray on the particle in vigorously dispersed and suspended conditions then the product dried to form pellets of defined granules size.
How to prepare Effervescent Granules?
Here two methods followed-
Fusion method
Wet Granulation method
Fusion Method
The method, where equivalent molecule of Water and Citric Acid present[One Molecule of water in each molecule of Citric Acid] act as binding agent for Powder. First of all the Citric Acid Crystals are made powder then this powder mixed with other powder. Same sieve size to be ensure to get uniform powder mixture. The mixing equipment’s and the sieves are made of stainless steel to avoid effect of the acid
To avoid premature chemical reaction and absorption of moisture the mixing of powder performed rapidly in a low humidity area. Then the powder mixer transfer a suitable dish in an oven which temperature between 34°C to 40°C. Use heat resistant spatula to turn the powder. During this process, the heat release water of crystallization from Citric Acid which dissolve a portion of this power mixture and initiate chemical reaction produce Carbon Dioxide cause the soften of powder mass. Then the powder become to extend spongy and this spongy powder then rubbed through a sieve to produce desired size granules.
Various size of sieves are available in the market produce different size of granules e.g. No. 4 sieves use to produce large granules, No. 8 sieves use to produce medium size granules and No. 10 sieves use to produce small granules. To get best result during storage the granules are dried below 54°C and rapidly placed in container just after drying and tightly sealed.
Wet Granulation Method:
The wet granulation method is different from that of the fusion granulation method as water didn’t come from crystal stage of materials and additionally water to be added moisten the granules. Here all materials remains anhydrous until addition of water. After addition of water the prepared mass are then dried to prepare desired granules.
Shelf life and storage:
The Shelf life of the granules is 2-3 weeks. Granules should be stored in double layer polybag in airtight containers, add silica gel pouch outside the container to get proper result. Must be stored in cool and dry place and protect from direct sunlight.
In this way Powder and Granules are very essential to our day to day life. Powder and granules are consider the important part of pharmaceutical preparations. Special precaution may requires during manufacturing of powder and granules. This is all about the short brief description about Powder and Granules.
Difference between Powder and Granules, Definition of Granules:
Difference between Powder and Granules, Granules: It is the aggregations of small particle of power varies in size between 0.2 and 0.4 mm depending on their subsequent size. When granules are used as Tablet and Capsules, their size may vary from 0.2 and 0.5 mm.
They are generally spherical in shape but size may be change based on varies size reduction process. In pharmaceutical industry, the powdered particles are combined to form bigger one is known as granules which is used I various pharmaceutical compounding.
Powder:
Difference between Powder and Granules, Powder: The power can be defined as a dry bulk solid composed of fine particles and free flowing on shaken or slanted. This is the special type of granules but the term granules and powder used to distinct different type of materials. Actually powder means very fine particle and granules means larger coarse particle. Powder refers to the finer particle compare to granules.
Due to particle size variation powder shows lower flow property and the granules shows the higher flow property. Due to small particle size the power easily form clumps when start flowing and granules generally tend to form clumps, only when we wet the granules then it form clumps.
The particle form granules then the segregation of granules tend to less compare to power. The granules can easily withstand in atmosphere upon standing in long time but powder can’t stand long tine in this condition. You can wet the granules in more easy way by liquid solvent. Various types of dry powder products are available in the current market which further made solution and suspension upon addition solvent. Generally powder in pharmaceuticals company considered in solid dosage form which may contains medicinal or non-medicinal [Excipients] ingredients use for external or internal purpose. The pharmaceutical powder may be obtained from comminuting, grinding and crushing. The particle size of the powder may vary from 10 nm to 1000 μm.
In the modern history the usage of powder is increasing day by day in various field mainly in chemicals, cosmetics, foods and pharmaceuticals. The most of the pharmaceuticals dosage form administer as solid stage dosage form which is mainly prepared by powder [Granules] by means of various ways as processing and formulations.
The widely used pharmaceuticals dosage form is tablets and capsule. The usage of powder has been replaced by the widely used pharmaceuticals dosage form, Tablets and Capsule. That is the most traditional form of medicine continue to use this dosage form until today and continuing.
Difference between Powder and Granules?
Powder
Granules
Any distinct/discrete particles having size less than 1000 µm is known as Powder.
Aggregations of small particle of power varies in size between 0.2 and 0.4 mm known as Granules.
Having higher cohesive strength due to fine particle.
Having lower cohesive strength due to coarse particle.
Flow property is very low compare to granules and not suitable for tablet compression.
High flow property compare to Powder can produce uniform tablet weight.
During compression this can be separated if it contains different ingredients.
Less chance of separation during compression though it contains different ingredients.
Due to high cohesive strength, it forms high density layer at the upper portion create weight variation during compression.
Due to low cohesive strength, it forms uniform layer in every portion produce less weight variation during compression.
Air may entrapped during compression of tablets increase capping tendency.
Less chance of air entrapping during compression so significantly reduce capping tendency.
It may be blown from the die and cause frequently sticking problem during tablet compression.
It can’t blown out from the die so less chance to cause sticking problem during compression.
The Flow-Function[FF] value is lower limit, so it shows low flow property on hopper.
The Flow-Function[FF] value is higher limit, so it shows high flow property on hopper ensure smooth operation
It requires steeper hopper angle to ensure flow property.
Not require to steeper hopper angle, work well in any suitable hopper.
Not suitable for compression tablet, Encapsulation process, may be used for dry solid preparation which further tend to form solution and suspension upon addition of solvent.
Very much suitable to compress tablet and Encapsulation process, produce uniform tablet and Capsule
Advantages and Disadvantages of Pharmaceutical Powders
Advantage of Powders
Pharmaceutical powders offer numerous benefits to the pharmaceutical industry.
Ease of administration: Powders can be formulated into various dosage forms such as tablets, capsules, suspensions or solutions, making them versatile for oral, topical or inhalation administration.
Better solubility: Some drugs are poorly soluble in liquid form but can be soluble in powder form, increasing bioavailability and therapeutic efficacy.
Dosage flexibility: The powder allows precise dosage control and allows the dosage to be adjusted according to the patient’s needs. This is particularly useful in pediatrics and geriatrics where dosage adjustments may be necessary.
Stability: Many pharmaceutical powders are more stable than liquid formulations because they are less susceptible to chemical degradation or microbial contamination.
Longer Shelf Life: Properly manufactured and stored powders have a longer shelf life than liquid formulations, reducing the frequency of production and replenishment.
Easier to transport and store: Powders are often lighter and more compact than liquid formulations, making transport and storage easier and less expensive, which can be particularly useful in resource-limited environments.
Flexibility in formulation: Pharmaceutical powders provide flexibility in formulation development by mixing various excipients to modify release kinetics, improve taste, increase stability or facilitate administration.
Reduced risk of spills and leaks: Unlike liquid formulations, powders are less likely to leak or leak during transport and handling, reducing waste and potential safety hazards.
Customization: Powder formulations can be customized for patients with specific requirements such as: B. Patients who are allergic to certain ingredients or who require special dosage forms such as powders for reconstitution.
Cost-effectiveness: In some cases, manufacturing pharmaceutical powders can be more cost-effective than manufacturing liquid formulations because the manufacturing process is simpler and packaging requirements are less.
Pharmaceutical powders are the preferred dosage form for many drugs in the pharmaceutical industry as they offer numerous advantages in terms of delivery, stability, flexibility and cost-effectiveness.
Disadvantages of Powders
Like any other drug, pharmaceutical powder also has its drawbacks. Some of these are:
Limited comfort: Powders often need to be measured and mixed with water or other liquid before ingestion, which can be particularly uncomfortable for patients with mobility or dexterity issues.
Dosage Accuracy: Ensuring an accurate dosage can be difficult with powders as slight differences in measuring or mixing can result in inaccurate dosage delivery.
Stability: Some pharmaceutical powders may have stability issues, especially if they are sensitive to humidity, air, or temperature. This may affect its lifespan and performance.
Palatability: Many pharmaceutical powders have an unpleasant taste or texture, making them difficult for patients to swallow or ingest.
Storage: Powders may require specific storage conditions to maintain stability and potency, such as: B. Cool, dry environment or protected from light.
Dosage Flexibility: Powders do not offer the same level of dosing flexibility as other dosage forms, such as tablets or capsules, which may limit their usefulness in certain situations.
Accidental inhalation: There is a risk of accidental inhalation when handling powders, which can be particularly dangerous for some medications.
Manufacturing Challenges: Manufacturing pharmaceutical powders can be complex and require specialized equipment and processes, which can increase manufacturing costs.
Packaging: Powders may require special packaging to ensure proper control and dosing, which can increase production costs and have environmental impacts.
Patient Compliance: Some patients may have difficulty adhering to the regimen of measuring and mixing powders, resulting in medication compliance issues.
Powdered pharmaceuticals can be effective for drug delivery, but they also have some disadvantages that must be carefully considered when choosing the appropriate dosage form for a patient.
Pharmaceutical granules offer many advantages over other dosage forms such as tablets or capsules. These benefits include:
Enhanced solubility: Granules can be designed to increase the solubility of poorly soluble drugs, thereby improving absorption and bioavailability.
Dosage uniformity: The use of granules allows better control of dosage uniformity, ensuring consistent dosing for patients.
Taste masking: Granules can be coated or formulated to mask unpleasant tastes or odors associated with some drugs to improve patient compliance, especially in children and adolescents.
Formulation Flexibility: Granules provide flexibility in formulation design, allowing the inclusion of multiple active ingredients, controlled release formulations, or combination treatments.
Stability: Granules can improve the stability of some drugs by protecting them from degradation due to environmental factors such as humidity, light, or oxidation.
Ease of administration: The granules can be conveniently administered by mixing them with food or liquid, making it suitable for patients who have difficulty swallowing tablets or capsules.
Reduced risk of underdosing: Granules allow the full dose of drug to be released quickly, reducing the risk of underdosing, which may cause side effects or treatment failure.
Customization: Granules can be customized to specific patient groups such as: b. Pediatric or geriatric patients can adjust the size, flavor, or properties of the formulation to suit their needs.
Improved dissolution rate: Granules with optimized particle size distribution can have a higher dissolution rate, resulting in faster onset of action and better therapeutic results.
Ease of production: Granules can be produced using a variety of techniques such as extrusion, spheronization or spray drying, allowing for scalable and cost-effective production.
Overall, pharmaceutical granules offer versatility, precision, and improved performance compared to other dosage forms, making them an attractive option for drug delivery in a variety of therapeutic areas.
Disadvantages of Granules
Like other pharmaceutical formulations, pharmaceutical granules have disadvantages. Here are some potential pitfalls:
Limited solubility: Some pharmaceutical granules may have limited solubility, which may affect absorption and bioavailability in the body. This may cause the potency and effectiveness of the drug to vary.
Uniformity Issues: It can be difficult to achieve uniform granule size, shape and distribution of the active ingredient, especially in large-scale production. Inconsistent dosing and effects may occur.
Stability issues: Granules are more prone to disintegration and instability than other dosage forms such as tablets or capsules. Factors such as humidity, temperature, and light exposure can affect the stability of active ingredients.
Difficulty in handling: Granules can be more difficult to handle than other dosage forms, especially in terms of packaging, transportation and administration. Handling and processing may require special equipment and skills.
Palatability: Some granules have an unpleasant taste or texture that may reduce palatability for patients, especially children or those who have difficulty swallowing. This may affect patient compliance and medication taking.
Dosage Flexibility: Granules may not offer the same level of dosing flexibility as other dosage forms, such as tablets or liquid formulations. Dosage adjustments may require reformulation or changes in manufacturing.
Cost: The development and production of pharmaceutical granules can be expensive, especially if special equipment and processes are required. These costs can be passed on to consumers, making drugs more expensive.
8. Regulatory Issues: Regulatory approval for pharmaceutical granules may require additional data and documentation compared to traditional dosage forms. This may increase the time and resources we spend developing and marketing our products.
Environmental Impact: The production of pharmaceutical granules can generate waste and pollute the environment. This is especially true if solvents or other chemicals are used. Proper disposal and environmental management are important aspects.
Overall, pharmaceutical granules offer several advantages, such as improved bioavailability and dosing flexibility, but there are challenges and drawbacks that must be carefully considered during product development and use.
Frequently Asked Questions in VIVA, Here are some questions which are asked almost all type of VIVA
Note: All questions-answers are depicted here, those questions answer are explanatory/descriptive and link is given here. Click the link, you will get the answer. Only Short answers are given here otherwise you have click the link for descriptive answer.
Q-01: Tell me about yourself?
Answer: When answering the typical “tell me about yourself” interview question, it’s important to write a compelling, concise description that highlights relevant skills, experience, and accomplishments. Here’s a structured way to write a response:
Introduction: Start with a brief overview of your professional background and current position. for example: “Of course I would like to see my background. I have a bachelor’s degree in [your field] from [university] and have been working in [your industry/field] for [X years]. I am currently [your current position or role].”
Professional History: Highlight the milestones and experiences that have shaped your career. Focus on accomplishments that demonstrate your qualifications for the position you are applying for. Examples include: “Throughout my career, I have had the opportunity [to mention notable achievements or roles]. For example, while previously working at [Company Name], I led the project [Describe a successful project or initiative]. [Specify relevant skills] This experience has allowed me to hone skills that will be invaluable in this role.”
Skills and Strengths: Discuss your key skills and strengths and highlight those that fit the job requirements. Provide specific examples to illustrate each point. for example: “I’m just as good at [citing specific skills or strengths] as I am at [giving examples]. While working at [previous company], I was praised for my ability to [describe relevant skills or strengths], which led to [positive outcomes], such as B. increased efficiency or sales.”
Passion and Fit: Finally, express your enthusiasm for the opportunity and how your background aligns with the company’s mission or values. Show genuine interest in the position. Examples include: “I really welcome the opportunity to [mention your passions or interests] and [mention specifics about the role or company]. I appreciate [company name]’s efforts to [state relevant values or initiatives], and my expertise in [your core competencies] will help you [state how you can contribute to the company’s goals] I believe this can be done. “
Conclusion: Ends the discussion with an open invitation to further discussion or questions. “I’m excited to learn more about how I can contribute to [company name]. Do you have specific questions about my background or experience?”
Tailor your answer to the position you are applying for, keep it short, and focus on the most relevant information. Practice ahead of time to ensure your responses sound natural and confident during the interview.
Final Answer
“Of course I would like to see my background. I have a bachelor’s degree in [your field] from [university] and have been working in [your industry/field] for [X years]. I am currently [your current position or role].”
“Throughout my career, I have had the opportunity [to mention notable achievements or roles]. For example, while previously working at [Company Name], I led the project [Describe a successful project or initiative]. [Specify relevant skills] This experience has allowed me to hone skills that will be invaluable in this role.”
“I’m just as good at [citing specific skills or strengths] as I am at [giving examples]. While working at [previous company], I was praised for my ability to [describe relevant skills or strengths], which led to [positive outcomes], such as B. increased efficiency or sales.”
“I really welcome the opportunity to [mention your passions or interests] and [mention specifics about the role or company]. I appreciate [company name]’s efforts to [state relevant values or initiatives], and my expertise in [your core competencies] will help you [state how you can contribute to the company’s goals] I believe this can be done. “
“I’m excited to learn more about how I can contribute to [company name]. Do you have specific questions about my background or experience?”
Q-02: Why do you work with us?
Answer: I decided to work for you for several reasons. They all align with my professional ambitions and personal values. First, your reputation for innovation and excellence in [specific industry/sector] is very interesting. I want to contribute to a team that continues to push boundaries and set industry standards.
Second, I am very impressed by your company’s commitment to [specific values or initiatives such as sustainability, diversity, community involvement, etc.]. I believe in aligning my personal values with those of the organization I work for and welcome the opportunity to contribute to meaningful initiatives that have a positive impact on the company and the wider community.
Additionally, I am truly impressed by the quality of your team and the collaborative culture that has been fostered here. I look forward to learning and working with talented people because I believe that collaboration and teamwork are essential success factors for any company.
Overall, I think working with your company is a personal and professional development opportunity. Here I can offer my skills and expertise and learn and develop in a dynamic and supportive environment. “I’m excited to join your team and contribute to your continued success and innovation.
Q-03: What is your strength?
Answer: When asked what my strengths were, I emphasized my adaptability and ability to learn quickly. Throughout my career, I have faced a variety of challenges and tasks that have required me to quickly understand new concepts, techniques, or methods. This adaptability has allowed me to thrive in a fast-paced environment and contribute effectively to diverse teams. Additionally, I believe that excellent communication skills allow me to communicate complex ideas effectively and collaborate with colleagues to enhance my abilities in any role. Overall, I think adaptability and communication skills are my biggest strengths. This allows you to tackle any project or problem with confidence and competence.
Q-04: What is your weakness?
Answer: As I progressed in my career, I realized that I tended to be overly critical of my work. This has led me to strive for excellence and continually strive for improvement, but I’ve also learned that it’s important to balance that with acknowledging my accomplishments and being kind to myself. To solve this problem, I started implementing strategies like setting specific goals and objectives, asking for feedback from others, and celebrating successes along the way. Not only has it helped me perform my role more efficiently, but it has also helped me maintain a healthy work-life balance.”
This response acknowledges weaknesses (without being overly critical) by highlighting the steps taken to address them and demonstrating the candidate’s commitment to personal growth and development. It also emphasizes positive traits such as confidence, resilience, and a proactive approach to self-improvement.
Q-05: Why we should hire you?
Answer: “I believe my combination of skills, experience and passion will make me the perfect person for this role and a valuable addition to your team. I have honed my skills in [a specific skill or specialty] with [X years/months] of experience in [your field/industry].
What sets me apart is my proven track record [mention notable accomplishments or accomplishments relevant to the position]. I am also adaptable and thrive in fast-paced environments, as evidenced by my ability to lead by example in successfully managing challenging situations or projects.
Additionally, I am truly excited for the opportunity to contribute to the mission and goals of [company name]. I am committed to bringing my unique perspective and innovative ideas and collaborating with my colleagues to drive success and exceed expectations.
Overall, I am confident that my skills, experience and passion make me the ideal candidate for this position and I welcome the opportunity to contribute to the continued growth and success of [company name].”
This answer effectively highlights your qualifications, accomplishments, and passion for the position and demonstrates why you are the best person for the job.
Q-06: What do you know about our company?
Answer: “Prior to this interview, I did a lot of research about your company and was really impressed with what I learned. You continue to enjoy a reputation for innovation and excellence in [specify specific industry or specialty]. Setting a new standard. I was particularly attracted to [specify relevant aspects such as technology, sustainability or community] because of the impact of your recent [specify specific project, product or initiative] and also [specify relevant aspects such as technology, sustainability or community]. “I see your commitment to [or the principles the company emphasizes, such as diversity and inclusion, environmental sustainability, and customer satisfaction] that align perfectly with my professional values and have a huge impact on the organization.”
Q-07: Why do you want to leave your current company?
Answer: When asked why I want to leave my current company, I see this as an opportunity to highlight what I’m looking for in my career rather than just focusing on what I want to leave behind. Although I have enjoyed my time at my current company and the experience I have gained there, I believe now is the right time to explore new opportunities that are more aligned with my long-term career goals and aspirations. I am looking for a role that offers greater challenge, opportunities for growth, and greater alignment with my professional values and interests. After careful consideration, I have concluded that this position is the ideal next step for me. This allows me to further develop my skills and make a meaningful contribution to teams and organizations that share my vision for success.
Q-8: What is your salary expectation?
Answer: When asked about my salary expectations, I respond by expressing my willingness to negotiate a salary that is fair and reflects the value I bring to the job and the organization. I understand that compensation is determined by a variety of factors, including the responsibilities of the position, company budget, and industry standards.
Ideally, I’m looking for a compensation package that matches my skills, experience, and market price for similar positions. Can you tell me more about the salary range for this position or the typical compensation structure within your company? This will help you better understand the parameters and reach a mutually beneficial agreement.
Q-9: What is your career objective?
Answer: “My career goals are to continue to grow and develop in my field and utilize my skills and experience to make meaningful contributions to the organizations I work for. In the short term, I want to excel and master the role I am applying for.” Create responsibilities and add value where possible. Looking to the future, I seek to take on more responsibility and eventually reach a position where I lead a team. Strategic initiatives “I can lead and drive and have a positive impact on the growth and success of the company. Ultimately, my goal is to continually learn, innovate and contribute to both personal and organizational growth.”
Q-10: Why You are Interested in this Position?
Answer: “I am very passionate about [the position or some aspect of the company] and this role is a perfect fit for my skills, experience and career goals. I’ve been following your company for a while and have been impressed by your commitment to [mention company-specific values, innovations, or achievements].
I also think this position is an exciting opportunity to [state specific goals or challenges associated with the role], which is incredibly motivating. I thrive in an environment where I can use [benchmark-related skills or strengths] to make a meaningful impact, and I believe this role does just that.
Additionally, I am very excited about your company’s growth potential and learning opportunities. It is important to develop yourself professionally while passing on professional knowledge. Overall, I am very excited about the prospect of joining your team and contributing to the continued success and innovation of [company/sector/industry].”
This response demonstrates passion for the job, alignment with company values and goals, and a focus on personal and professional growth within the position. This is all about the Frequently Asked Questions in VIVA.
Currently I’m looking for an opportunity to utilize my attained skills and working out to assist the company to achieve goal and my future career advancement. I want my hard work to make a substantial difference to the company and help in their subsequent success stories.
Experience
Now I’m working as Officer Quality Assurance at XYZ Pharmaceuticals Ltd from May 20xx to till now.
[Omit this section, if you are Fresh employee]
Key job responsibility
In-process control
BMR/BPR issuance
Batch Compilation
Sampling of Products
[Omit this section, if you are Fresh employee]
Education Qualification
Master of Pharmacy [Mpharm]
Institution: ABC University
Duration: 20xx to 20xy
Result: 3.50 out of 4.0
Bachelor of Pharmacy [Bpharm]
Institution: ABC University
Duration: 20xx to 20xy
Result: 3.80 out of 4.0
Higher Secondary Certificate
Institution: ABC College
Year: 20xx
Group: Science
Result: 4.80 out of 5.00
Board: DEF
Secondary School Certificate
Institution: ABC High School
Year: 20xx
Group: Science
Result: 5.00 out of 5.00
Board: DEF
In-plant Training
I have completed my internship training in ABC Pharmaceuticals limited for four weeks in the year of 20xx.
Project work
I have submitted my project report on “Evaluation of analgesic, neuropharmacological and cytotoxic activity of Trigonella foenum-graecum Linn” presented to the department of the pharmacy at UOK under the supervision of Dr. XY Petersen professor, UOK.
Computer skill
Microsoft Office Suite
Basic Computer Skill
Internet Surfing
Basic Hardware Maintenance of Desktop PC
Adobe Graphic Suite
Language Skill
Have proficiency in English and French both in writing and reading
Personal Information
Father Name: Peter Francis McGrath
Mother name: Cristina Paris
Date of birth: 19xx
Gender: Female
Reference
1. Professor HC Peter
Faculty Head, UOK
2. Professor YK Demes
Head of Pharmacy Department, UOK
I, hereby, declare that each of the information cited above is true and any intentionally made mistake will result me in disqualification.
Application for the post of Officer, Quality Assurance, you can follow the following template for the mentioned post-
28th May 20XX
To
Manager
Human Resource & Development
ABC Pharmaceuticals Ltd.
121, Lakeshore Area, XYZ-700001
Subject: An application for the position Officer, Quality Assurance
I would like to express my interest and qualifications after seeing the job posting for the position of Quality Control Manager at your famous pharmaceutical company posted on xyz.com.
Throughout my career, I have consistently demonstrated a commitment to superior quality management through timeliness, dedication, integrity, effective team-building skills and a strong professional attitude.
For example, while working at [previous company], I led a project to optimize the quality control process, which resulted in a 20% improvement in product reliability and customer satisfaction. This initiative demonstrated not only my attention to detail, but also my ability to work with cross-functional teams to achieve organizational goals.
Please see attached resume and current color photo. If you have any questions or would like to schedule an interview, please feel free to contact me at 01XXXXXXXXX02. I welcome the opportunity to contribute to your team and am confident that I can excel in the role of QA Manager.
Sincerely Yours
Isabella Paris
Application for the post of Officer, Quality Assurance: That is the basic format.
“Why are you interested in this position?” Frequently asked questions during interviews often surprise job seekers. However, this is an important question that reveals your motivation and passion for the job. Let’s dig deeper and use real-life examples to explain why this question is asked and how to answer it honestly, positively, and effectively.
Employers ask this question to determine whether your interest in the job is genuine and whether your skills and aspirations match the position. Imagine a scenario where you apply for a marketing manager position at a technology startup. The interviewer wants to understand why you are attracted to the position and how you believe you will contribute to the growth of the company.
To write a compelling response, it’s important to tailor it to your specific role and company. Start by expressing your genuine interest in the position and mention things like the company’s innovative marketing approach or its goals for disrupting the industry. For example, mention your passion for using new technologies to run targeted marketing campaigns that align with your company’s forward-thinking ethos.
Next, highlight the unique skills and experience you have and look for similarities between the responsibilities of your current role and your desired position. Let’s say you are currently a digital marketing specialist at a traditional advertising agency. You may also express a desire to move into a leadership role where you can drive a comprehensive marketing strategy while leveraging data analytics and campaign optimization skills.
Additionally, demonstrate your willingness to take on new challenges and make a significant contribution to the role. Share past projects or success stories that demonstrate your ability to innovate and achieve results. Perhaps you’ve led a cross-functional team to launch a successful social media campaign that significantly increased brand awareness and engagement metrics.
Ultimately, your answer should convey a genuine passion for the role and a clear idea of how you can contribute to the company’s success. By aligning your interests with the job requirements and expressing your value proposition effectively, you can make a lasting impression on the interviewer and increase your chances of getting the job.
The application format may vary depending on the employer, but the basic goal is the same: to assess motivation and suitability for the job. Approach each interview with preparation and authenticity, personalizing your answers to highlight your strengths and fit the role.
Why you like our company?
What part of the job role you like most?
Are you interested to take the new role?
Why you are interested to take the new role?
Which part of the job is interesting to you?
Tell us why you are interested this position?
All of those questions contains the same answer. Now, we will discuss how we can prepare the best answer for this question” Why are you interested in this position?
“Why are you interested in this job?” Why employer ask this question?
As part of the employment evaluation process, employers often ask leading questions with the intention of broadly assessing several important aspects to comprehensively determine a candidate’s suitability for a particular role. This multi-faceted test will give you an idea of the complexity of the position, your true passion for the role, your possession of the required knowledge and experience, and your potential positive impact on the overall success of the company.
Imagine a scenario taking place in a dynamic software development company that carefully selects candidates for project management roles. In this context, interviewers look for a candidate’s deep knowledge of the software development lifecycle and assess his or her familiarity with agile methodologies and related tools. To capture genuine engagement and interest, conversations strategically include emotional questions and highlight trends in team collaboration and innovation.
An essential part of this evaluation process is reviewing the candidate’s performance. Particular emphasis will be placed on previous experience successfully managing projects and competently handling problem-solving situations. This historical perspective allows interviewers to assess a candidate’s suitability based on practical knowledge and skills acquired over time. As the interview progresses, discussions will explore the candidate’s strategic vision and ability to lead the company toward tangible, positive results, including increased productivity, improved customer satisfaction, and timely completion of projects.
Essentially, employers are looking for candidates who not only meet the company’s immediate needs but also demonstrate a proactive attitude toward ongoing personal and professional development. Valuation is not just a transaction. This extends to those who actively contribute to the company’s success and continually look for opportunities to develop further. This symbiotic relationship between individuals and organizations develops further when candidates actively contribute to the company’s success and pursue opportunities for continuous improvement. This collaborative approach promotes a win-win dynamic and creates an environment where both the organization and its employees can develop and grow together.
“Why are you interested in this role?” How to prepare answer?
We have to maintain some steps to create the best answer for this positions. Follow the descriptive points, we will prepare a best answer-
Collect information about the company
First of all read the job description carefully and surf the internet to collect the basic information about the company. Almost all company have a website, where you will get the all information that you want. Basically learn their business standard, mission vision, working environment, employee facility, product and service but not so much deep.
If you can express your know how at the interview session for the company, surely you will get better preferences at the interview session. The interviewer will show the positive response to you, they will start thinking that you are interested to play the new role.
Organize your answer and try to memorize the keyword
When you complete the research about the company then you can start your answer preparation considering several points-Is this role is relevant to your experience? Is it help your career advancement process? What is the most unique point of this job? Organize your answer one step another then you can step forward.
Add a question at the end of the interview
When you think that the interview are about to end the try to ask a question to the interviewer about the most relevant topic to the job description this will create a two way facility that you are more interested to the job and the interviewer will think about you that you are very much interested about the role. Try to avoid any unnecessary questions. It will be better to keep silence without bother the interviewer by your immature questions.
Following are some example about “Why are you interested in this position”
Quality Control Manager
For over 10 years I have been committed to contributing to the success of my current employer, where I find great satisfaction in my role as a manager and leading a team of 20 employees. The experience I have gained over the past 12 years has been invaluable in shaping me into a professional ready to take on new challenges and greater responsibilities.
After receiving your latest newsletter, I am very excited to be taking on a leadership position leading a team of over 50 employees. This opportunity fits perfectly with my professional development ambitions and allows me to leverage my extensive leadership experience to have a greater impact on the organization.
As I look forward to transitioning into this new role, I am interested in understanding the different types of teams within an organization and the specific managers associated with them. Gaining insight into the dynamics and responsibilities of these teams will undoubtedly enhance your effective leadership abilities and contribute significantly to the overall success of your organization.
You may use specific examples from your current position to illustrate your preparation for this role. Over the years, I have led teams that successfully launch innovative projects, resulting in measurable improvements in productivity and overall team morale. This experience not only improved my leadership skills, but also gave me a solid foundation to tackle the complexities of leading large teams.
Lastly, I am excited about the prospect of leading a team of 50+ people. I am committed to understanding the different team structures and each supervisor. This knowledge will enable you to accurately lead and contribute meaningfully to the continued success of our organization.
Quality control Analyst
In my current role, I actively contribute as a team player and work collaboratively to get work done. However, opportunities for professional development and role expansion are limited in your current position. After reviewing your latest circular, it has become clear that the open position fits my ambitions perfectly and provides an ideal platform to expand my professional skills by working with cross-functional team members.
For example, in my current role, I have successfully collaborated with colleagues on multiple projects, demonstrating my ability to work well in a team. Despite my commitment to teamwork, I would like to have a broader role where I can work on a variety of projects and interact with professionals from different departments. The advertised position not only reflects my skills, but also promises an environment that fosters cross-departmental collaboration and leverages existing skills while acquiring new ones.
Given my passion for my future role, I would like to know how your company creates an environment that supports employee engagement. Can you provide information about opportunities and initiatives to ensure employees, especially those working in cross-functional teams, feel valued and supported in their professional development within the organization?
What Makes You Unique ? the way to get a new job is obviously to submit an application to the respective organization to their mailing address by email or offline mailing system like FedEx or various courier service but the more interesting thing is that thousands of same qualified employee applied for a single position. Do you really have any chance to get the job? Simply the answer is NO.
Yes, you can’t expect the job if you didn’t possess anything that will be unique from others. Why interviewer choose you? You are so smart or you are very good to look at, that’s are personal belonging not fit to get a job actually. You have to meet the job criteria actually.
A person with typical qualification is hard to fight with the other job seeker if he didn’t possess extra thing. What is this extra thing? In this session we are going to learn about this extra thing!
When thousands of employee apply for the same post this is very natural that your qualification will overlap with other job seeker and this time you have to find out which criteria you possess that fit with the applied job makes you unique from others.
In the interview session, the interviewer may ask you the familiar question “What make you unique?” Take this opportunity, give your answer in more specific way with full confident and accurate result. Be honest at your answer so interviewer can trust you and they can realize that you are really bring some the benefit for their organization. So let’s go, how we can make this question answer.
“What makes you unique? “Why frequently interviewer ask this question
The very first reason is to ask this question is, the interviewer just want to identify the employee who is the best fit for the role compare to other candidate they are interviewing. This can be simply say that why you not others where nearly all of the candidate possess the same qualifications.
Secondly the interviewer want to know that how you are evaluating yourself. They can realize that which thing you are emphasize at your interview session. If you able to emphasize the point that the interviewer really asking for the role then you can go with it. The employer want strong mentality but basic skill person which may not include with your application.
How to prepare you for the question
I think this is very difficult to identify anything which is really make you different from the other candidate. So let it go, prepare with your experience, focus on your strength which can increase your strength. Explain how interviewer will be benefited to hire you. Use your relevant background which is best match for the job. You can express your specific background that is really relate with this job.
Realize the interviewer asking about the positions
All of the interviewer always like the employee who will possess right skill set, perspective, ability to achieve target at every situations. So take time and think that are you really fit for the job. Read the job description completely, if you get any keyword then that is the best match for you then prepare yourself with that questions which point the interviewer may find effective if you properly deliver it.
Focus on your previous achievement
In professional life, you may be experienced with so many unwanted situations and bring back it normal. Some problem may be more challenges and some are not. Note the point where you face more challenges and how you overcome that. Relate this similar problem that me helpful in interview session.
You present those example where you were the key person no other colleague. Professional experience where your involvement was minor doesn’t require to mention in interview session, this will prove that you are unable to handle the situation.
Deliver the specific type of example which is more relevant with your work, try to create it more realistic rather than descriptive.
For example, “You are able to handle customer complaint and recently you have receive an interesting complaint and you have solve this issue and create a new facility/process/method to do the same. You can share this experience here”
Expression may be, ”Two month ago, I received a complaint about one of our new product that the customer received empty blister contains one tablet less out of ten tablets in a blister. I investigate the matter and find out that the pocket of all blister is same except one. During automatic filling process one tablet can to be filled due to small size of the pocket. Then we change the pocket size questing the supplier and include weight checking after blistering process. Now we are not receiving this type of complaint anymore”.
Highlight your most popular criteria
Try to mention your more strength point which your previous employees are appreciated and you can apply the same here will facilitate your job role. You can express “How other people know your patience and dedication to your professional life and how you face the hard situation in high stress situation, also mention your dedication during unfavorable condition”.
Never try to show your unique experience
Every employers are searching for the best for the best not a person contains unnecessary skill which is not relevant with the job description. Try to avoid the unnecessary skills which will bother the interviewer.
For example, “If you are applying for a position for Warehouse Officer, the interview panel is not interested that your good at website design and development, this is totally your personal matters not relevant to your applied position”.
Here is some example “Tell us what makes you unique”
“To organize & labelling something will save the time and space is my moto in the professional life. After joining of the current office as Quality Assurance Officer in document section, I made a list of our document as per product category in alphabetic manner at excel tracker with proper labelling has decrease the hassle during tracking of the product. It has been save our time and organized our working environment”
“My ability to make easy and smooth communication to my peer’s colleague and rapport building with them make me more unique in my professional life. As Admin Officer, I start a WhatsApp group and start connecting to the relevant colleague who are looking for quick admin support regarding transport and emergency hospital support. I want to spread my service and profession will help the others who are really feels their demand to be filled up quickly. I can easily identify the pain points of the employee and their challenge to acquire it”.
Every employee contains some inner traits that he can’t realize properly what makes him unique. If he able to identify the criteria and properly deliver it at the interview session will bring a better result for the employee.
Criteria of effective feedback
When it comes to providing effective feedback during an interview, there are several key principles that, if followed, can significantly improve the quality and impact of the feedback provided. Let’s take a closer look at the individual principles and expand on them using real-world examples.
Explain in detail
Focus on behavior
Balance positive and negative
Provide constructive criticism
Encourage self-reflection
Maintain professionalism and empathy
Follow-up
Explain in detail:
Instead of giving general comments, drill down into the details by providing specific examples and observations. For example, instead of saying that the presentation lacks depth, you could provide simple feedback such as “The presentation lacks data to support the financial projections, making it difficult for the audience to understand the feasibility of the strategy.”
Focus on behavior:
It is essential to focus on feedback on observable behavior rather than judgments about individual characteristics. For example, instead of accusing someone of being “disorganized,” you might say, “During a project meeting, you failed to set a clear agenda and assign tasks, causing confusion among team members.”
Balance positive and negative:
While it is important to address areas needing improvement, it is equally important to identify strengths and successes. For example, interview responses can not only point out areas for improvement, but also praise the candidate’s strong communication skills and insightful approach to problem solving.
Provide constructive criticism:
Feedback should not only highlight areas needing growth, but also provide actionable suggestions for improvement. For example, if you are criticizing a candidate for answering a difficult question, you can express your constructive criticism by suggesting specific strategies to improve the answer, such as: b. Include relevant examples or improve your presentation.
Encourage self-reflection:
Encouraging respondents to reflect on their feedback promotes a culture of continuous learning and improvement. For example, after providing feedback on a candidate’s performance in a mock negotiation exercise, you might ask the candidate to reflect on his or her approach and consider how he or she might apply his or her strategies in a similar situation in the future.
Maintain professionalism and empathy:
Feedback should be provided in a way that maintains professionalism and empathizes with the feelings of the interviewee. For example, when providing feedback to assess a candidate’s technical skills, you can provide constructive criticism in a polite tone without undermining the other person’s confidence or discouraging further effort.
Follow-up:
Following up with respondents after a feedback session demonstrates their commitment to growth and development. For example, after providing feedback on a candidate’s mock presentation, you might suggest scheduling a follow-up session to clarify any outstanding questions or provide further guidance on areas needing improvement.
By diligently adhering to these principles, interviewers can provide feedback that is not only valuable and constructive, but also helpful to the interviewee’s professional development.
Make a great impression on interview, this session may divided into three sections
Before starting interview session
At interview session
When you just complete your interview session
Before starting interview session
The very last day before seating your interview session, you have to arrange some time to do the same which will help you better to understand your situation.
Start Researching about the company
Start Practicing with common interview question
Get prepare according interviewer job Description
Follow PDCA cycle to answer the question
Execution of Plan
Collect appropriate references
Prepare with real life professional experience
Be proactive not reactive
Start Researching about the company
Make a great impression on interview, Now a days any established company possess a well-designed website contains all basic information regarding company mission, vision, target, goal, achievement, CSR[Corporate Social Responsibility], product and service list, Top management profile and overall summary of the company. Most of the company contains Social Media Profile, Page, and Group etc. You can start your research regarding the respected from here.
From the Facebook group and page, you will find the information regarding company culture, employee activities, management policy, press release etc. even you can find an old friend who are working in the company if you are like enough.
Start Practicing with common interview question
Tell me about yourself is the most common interview question, this question may arise different form like express yourself/Can you please tell your career goal/Summarize yourself/ Present yourself/Give me basic information about you/How can you express yourself and the answer same.
Another interview question is Why you choose our company/Why you leave your current company/Why we should hire you/ Give me some reason that you are the best of all/What is your salary expectation/Why you asking more salary/What is the negative side of your company?
You have to prepare align with the common interview questions. Hope this will help you during interview session.
Get prepare according interviewer job Description
Read carefully the complete job descriptions and qualification, job locations and related information so that the best result you can get. Mark the keyword of the job descriptions and match with your existing criteria if you are go well with that or not. Please don’t apply the job position which didn’t match with your criteria to avoid any unwanted occurrences during interview session.
You may want to print it out and begin underlining specific skills the employer is looking for. Think about examples from your past and current work that align with these requirements.
Follow PDCA cycle to answer the question
Make a great impression on interview, You have to use PDCA cycle to answer the questions. You have to exercise PDCA [Plan, Do, Check, Action] to answer the question. Plan your interview session, take necessary measure to execute the plan, Seek any error present or not, if found correct the error, then finally execute your plan.
Execution of Plan
After making a list of common interview question and necessary answer then you can engage your close friend as interviewer and start practice with questions and answer. More and more practice will increase your capability to deliver the answer. After a certain period of time your confidence will high and you will get the best result from this action.
Collect appropriate references
Before or after your interview, the interviewer musk ask you list of reference. So it will be the wise practice to collect list of referees before start the main interview session. This approach will also help you to facilitate the hiring process.
Prepare with real life professional experience
Make a great impression on interview, exercise with your best professional experience where you played major role and solve the issue with excellent solution. Deliver the answer if ask “What is best work of your professional life and how you solve that issue”. You can prepare your answer with your professional experience or volunteer works which praise more.
Be proactive not reactive
Today interviewers are very much smart, they just not only like to questions to the employee but also expect questions from employee. Create a list a smart questions bank is essential smart interview session. In the very past it was the common thinking that to ask question to the interviewer is a serious crime but today the scenario has been changed, the road has just change from one way.
Be sure what you are asking to the employer the approach at smart way-
Can you please explain the job description of this post?
Can you share a success store who has been a successful leader in the similar role?
How you will evaluate my position?
Have any opportunity to migrate cross functional department?
How I will get confirmation to my position?
Is this position allow team work or I have to standalone?
Who will assist me to perform the day to day activities?
At interview session
Make a great impression on interview, on the interview day you have to proceed your next activity as follows-
Be aware to prepare your dress code
Be aware about Interview accessories
Time planning to reach interview location
Make positive first impression
Keep your respect on everyone
Time to show you manner
Ready to show your positive attitude
Keep silence and avoid any unnecessary airy gesture
Use professional achieves with every answer
Give your feedback in short and concise
Be aware to prepare your dress code
If possible ask the interviewer for your dress code. Some of the company also mention their dress code via email and some are not. You can ask contact person about this issues. You can search internet about this issue” How to dress up for a formal interview?’’ Normally a black pant with white full shirt with neck tie and leather shoe was the trend in the past but most of the employee break the tradition wearing colorful full sleeve shirt, pant etc. A better looking spectacles can easily help to increase your personality.
Be aware about Interview accessories
Make it simple, just bring your recent resume, pen, PP size color photo, small notebook, ID card, highlighter and please avoid your smart gadget, you can bring smartphone but you have to keep it vibration otherwise keep it silent for the best. Try to maintain polite eye contact with the interviewer as much as possible.
Time planning to reach interview location
You can use google map to estimate the time to reach the spot of interview. It is the best practice to reach the location at least 30 minutes earlier. If you don’t know the location of the interview, feel free to contact with the contact person of the interviewer “How can you reach their location effetely, try to use personal transport or ride sharing service, avoid public transport for better preparation. If you use public transport, you must have a backup plan if traffic jam or closure or special occurrence.
Make positive first impression
Time to shine up your tiny expression- just make nails and teeth are clean enough, your cloths are stains, hole and extra thread free and lastly shine your favorite shoes. Show strong and confident body language that you are ready to take any challenge and keep your smile face during interview.
Keep your respect on everyone
On the interview location treat everyone with great respect. You should respect everyone security person to hiring manager, you didn’t know is actually hiring manager, plant manager and Quality head and so on. So keep your respect on.
Time to show you manner
Before enter into the interview room, ask permission to enter the room. Before the interview take a deep breathe to bring confident to you and avoid any negative fillings. When the interviewer extend their hand you have to firstly look their eye create a gentle smile and initiate handshake with them. A soft handshake is always preferable.
Ready to show your positive attitude
Nothing can, only attitude can win everybody heart. Deliver your most positive and specific answer what the ask not some much details. The interviewer must be beat you with series of questions to show their existence. You have to remain upbeat for a time being during interview session. Showing a positive answer with light smile face is always create a healthy interview environment.
Keep silence and avoid any unnecessary airy gesture
Keep at steady position and avoid any unnecessary body language, just focus on interviewer question, what he is asking to you? If you can’t hear or read the answer ask a repeat question politely ”Sorry, I can’t read you, can you please repeat the question”. If don’t know the answer of the asked questions, politely say” Sorry, I don’t know the answer of the questions exactly, can you please ask another question”
Use professional achieves with every answer
Try to answer any question with your practical professional’s achievements. If you can attach example with every answer then the interviewer will start to believe that you are the only one person who can solve their problem. Relate your answer with their requirements as per job descriptions.
Give your feedback in short and concise
Remember, your time in the interview session is very limited, so you have to answer in short and concise but informative and affirmative. Make your descriptive answer in short, only highlight on your answer keyword.
Keep your present job in positive side
Try to give your negative answer in positive way. Never underestimate or under value your current organization. Remember, no company like the negative person only want the problem solver not problem creator. Generally, company hire the employee when they face the tough situation to run their business.
Most of your answer must be consist of professional experience or something related with that but not personal comfort. Keep your eyes open if you receive any email or SMS or WhatsApp text. Generally you will get the result within one week to one month.
When you just complete your interview session
Make a great impression on interview, at the end of your interview, try to ask your hiring manager for the next steps. Most of the company inform by email for positive or negative result. Some of the company don’t send any rejection SMS or email or WhatsApp only inform if your selected for the next round.
Final communications
Never forget to collect ask business card from each interviewer for to send thank you email personally. If you face interview in morning session you have to send your email in evening and for other session send your thank you email in the next day but not to exceed 24 hours.
The content of the email must short and distinctive. Don’t send group email. You must be send the thank you mail separately. Generally all of the top management involve in interview session and they didn’t like group email at all from a job seeker. In this way you can make a great impression during interview session.
Factor affecting Great Impression on Interview
Making a compelling and lasting impression in an interview requires a careful mix of preparation, good communication skills, and solid professionalism. We dive deeper into preparation and explore a wide range of strategies, illustrated with real-world examples, that can significantly increase your chances of success.
Thorough company research
Introduction to resume
Common key interview questions
Workwear
Punctuality
Body language
Active listening
Express your passion
Thoughtful questions
Focus on soft skills
Post-interview follow-up
Thorough company research:
Learn about the company’s ethos, cultural differences, and overall mission. For example, if you’re applying to a technology company that promises innovation, demonstrate your ability to adapt to cutting-edge tools or methods. Understand the role and complexities of the sector. If you want to take on a marketing position at a fashion company, understanding the latest trends and market dynamics is essential.
Introduction to resume:
Prepare a brief discussion of the experiences, skills, and achievements described in your resume. For example, if you’ve worked on a successful project, be prepared to explain the challenges and accomplishments. Highlighting specific accomplishments that directly match the job requirements highlights your skills. If you are applying for a leadership position, discuss how your leadership has dramatically improved team performance.
Common key interview questions:
Guess and practice your answers to the most frequently asked interview questions. Using the STAR method, share a scenario where your innovative thinking led to a positive outcome. Tailoring responds to the specific requirements of the job. For example, if you’re applying for a customer service position, highlight an example of how you overcame a difficult situation with your problem-solving skills.
Workwear:
Choose attire that reflects the company culture and the position you are applying for. While a well-tailored suit may be appropriate in a corporate environment, a versatile style is desirable in creative industries. Your choice of clothing should reflect your understanding of your work environment. A graphic designer position may allow you to be creative, while a finance position may require a more conservative approach.
Punctuality:
Arrive on time to demonstrate your commitment to punctuality. This not only reflects your interest, but also provides margin in case of unexpected delays. Imagine a situation where a candidate arrives early due to an unexpected traffic jam. This proactive approach speaks volumes about their commitment.
Body language:
Demonstrate confident body language through consistent eye contact, a firm handshake, and upright posture. This can be described as a candidate who conveys confidence and approachability through body language, which are key characteristics for customer-facing roles. Using subtle body language, such as nodding your head in agreement or leaning forward slightly, can emphasize your participation in the conversation.
Active listening:
Demonstrate active listening by carefully answering the interviewer’s questions. An example would be a candidate who, when asked a complex question, takes time to organize his or her thoughts before giving a comprehensive answer. Avoiding interruptions and asking for clarification when necessary shows your commitment to clear communication.
Express your passion:
Express your genuine passion for the company and the position. When applying to a startup, explain how your passion for innovation perfectly matches the company’s ethos. Connecting your personal career goals with your business development can create a compelling story.
Thoughtful questions:
Prepare probing questions that explore business dynamics, team cohesion, and role complexities. An example of this would be a candidate trying to understand employee development or the company’s future vision during an interview. A thoughtful request shows your genuine interest and strategic thinking.
Focus on soft skills:
Emphasizes the importance of soft skills such as adaptability, teamwork, and effective communication. Share an example of how team spirit contributed to project success. In today’s dynamic workplace, employers value candidates who can integrate seamlessly into diverse teams.
Post-interview follow-up:
Send a personalized thank you email within 24 hours. Express your gratitude for the opportunity and reiterate your enthusiasm for the position. To enhance engagement, focus on specific aspects of the interview. A timely and thoughtful follow-up not only highlights your professionalism, but also ensures that you remain the center of the interviewer’s attention.
Simply put, excelling at interviews requires a holistic approach that goes beyond simple competencies. Integrating these skills with real-world examples not only increases your chances of success, but also sets you apart as a fully prepared and engaged candidate who is strategically aligned with your company’s vision and values.