Purified Water Generation Plant, Purpose:
Purified Water Generation Plant, The purpose of this SOP is to define the Manual Operation of Purified Water Generation Plant manufactured by Watertown in order to ensure its smooth & trouble-free operation and generation of qualified purified water.
Purified Water Generation Plant, Scope:
This Standard Operating Procedure applies to the PW plant manufactured by Watertown, which is located at the Utility area (roof top) of XX Pharmaceuticals Ltd.
Definitions / Abbreviation:
[][]SOP: Standard Operating Procedure.
[][]PW: Purified Water.
[][]HMI: Human Machine Interface.
[][]RO: Reverse Osmosis.
Responsibilities:
[][]The roles and responsibilities are as follows:
Engineering (Validation) Department
[][]Preparing the SOP and revise it when necessary.
Engineering (Maintenance) Department
[][]To provide necessary support for smooth operation of the system.
Operators
[][]To operate the PW plant according to the SOP.
Manager, Engineering
[][]To ensure that the operation of PW plant are done properly.
Manager, Quality Assurance
[][]To approve the SOP.
[][]To ensure overall implementation of this SOP.
Procedure:
Precautions:
[][]All operation work must be done safely in accordance with the requirements of the Plant Safety Statement and the safety notices around the plant. Specific attention must be paid to the following:
[][]Use Personal Protective Equipment during handling of any kind of chemical.
[][]Be careful about the hot water and steam line.
[][]Ensure all the utilities before doing any operation.
Operating Procedure:
[][]Manual operation of PW plant:
[][]Starting of PW plant:
[][]Switch on the main breaker to supply electrical power of the plant.
[][]Ensure compressed air and other utilities to run the plant.
[][]The HMI becomes ON and following screen will appear.
[][]Press Enter on that screen.
[][]Then the following screen will appear.
[][]Press “Parameter setting**” button to check the parameters and a box will appear for user ID and Password.
[][]Then the following screen will appear to see the parameters. Press “setting2” to see the other parameter settings.
[][]Then the following screen will appear.
[][]Press the “Pretreatment Flowchart” button and screen for pretreatment flowchart will appear.
[][]Press the “Manual off” button. In Manual mode the Multi Grade Filter and Active Carbon Filter will be reversely washed and then the RO will be washed by manually on Valve and pump. The softener generation also will be done manually.
[][]Reverse Washing of Multi grade filter:
[][]Active carbon filter reverse washing:
[][]Softener Regeneration:
[][]Manual Operation In RO:
[][]Press on RO Flow chart on Screen and will show following screen
[][]After 5-10 min on pump PU51-01,PU51-02,PU52
[][]Do reverse washing as it is stated for 3 minutes.
[][]Then open the valves XV51-09, XV51-06, XV52-10, XV52-09, XV52-06 and XV60-01.
[][]During Operation:
[][]To see any alarm press the “Alarm status” button in Figure 05. Following screen will appear:
[][]By pressing the button “ ” the alarms will be acknowledged and stored in the alarm history. All the alarms in the alarm history can be watched in the “History Alarm” section by pressing the Up and Down arrow.
[][]There is an online data logger which logs the conductivity of water after softener, 1st RO, 2nd RO and EDI.
[][]The real time curve can be seen by pressing the “Real Time Curve” button in Figure 05.
Stopping procedure of PW plant:
[][]To Stop Pump PU51-01,PU51-02,PU52
[][]To stop valves.
[][]After that press “Manual on” button in the “Pretreatment Flowchart status” screen (Figure 05) for stopping manual mode.
[][]Switch off the main breaker to cut the electricity.
[][]Close the line of compressed air and other utilities.
Annexure:
N/A